Three weeks in, and the picture has started to get a little clearer for the college football landscape, but there is still a long way to go. So heading into Week 4, there are plenty of big-time matchups that will have a major influence on the rest of the season.

Even more important than that though is that there are some very interesting betting opportunities for you and your pockets. So game by game, let’s break down some of the best lines for the big week ahead.

College Football Week 4 Spread Analysis & Match Up Overview

Betting odds are available week by week, and this slate has some great games and spreads you’ll want to consider when placing your bets. Here is a breakdown of some of the best games for Week 4.

Colorado Buffaloes at Oregon Ducks (Sept. 23rd)

Spread: Oregon -8

Analysis: The Colorado Buffaloes have quickly become America’s Sweetheart as the Cinderella Story of the season. Following a 1-11 outing in 2022, the team has taken the nation by storm, knocking off last season’s runner-up in TCU with a dominant offensive outing.

Colorado isn’t perfect, they’ve shown their flaws and still need to shore things up defensively, but they enter Saturday’s game 3-0 behind their stars QB Shedeur Sanders and WR/CB Travis Hunter with a huge task in Oregon to continue their path to perfection, can they pull it off?

Oregon also comes into this game undefeated and looks to be firing on all cylinders. The offense is capable of matching score for score behind QB Bo Nix, RB Bucky Irving, and WR Troy Franklin. However, the Ducks also have a strong defense to bring the balance required to put themselves ahead in big games like this one should be.

Writer’s Pick: Oregon -8

Colorado has proved to the country that they’re much better than the expectations placed on them, but that doesn’t mean they’ll be able to hold up all season. Oregon seems to have one of the more complete rosters in the country, and the defensive force to slow down the Buffaloes to not only win, but cover in the process.

>> Place your wagers at Bovada

Ohio State Buckeyes at Notre Dame Fighting Irish (Sept. 23rd)

Spread: Ohio State -7

Analysis: Ohio State entered the season with high expectations but things have simmered a bit with the offense not producing to expectations to this point. QB Kyle McCord has been serviceable, but there is still a lot left to be desired. However, with the offensive pieces they have with WRs Marvin Harrison Jr and Emeka Egbuka plus their RB tandem of Treyveon Henderson and Miyan Williams, the scoring seems like a when and not an if.

On the shoulders of QB Sam Hartman, the Fighting Irish come into this contest with plenty of excitement and hype surrounding their strong start to the season. The Fighting Irish have shown a nice amount of team cohesion that should hold up in big time contests like this one, but Ohio State will be a test bigger than any other they’ve faced to this point in the season. Will the luck of the Irish continue?

Writer’s Pick: Ohio State -7

The Buckeyes have been in this situation before where things start a little slow with a new quarterback, but that doesn’t last. Notre Dame looks stronger and more cohesive, but expect the Buckeyes to prevail in this one and escape with the victory. So, bet on Ohio State on one of our top picks!

>> Get the best odds for college football at MyBookie

Iowa Hawkeyes at Penn State Nittany Lions (Sept. 23rd)

Spread: Penn State -4.5

Analysis: After a 2022 season with abysmal offensive production, the Hawkeyes have seemed to find a bit of a spark behind Michigan state transfer QB Cade McNamara. As a result, they enter this one 3-0 with a chance to pull off a big victory and in a great spot to contend for the Big Ten West Division. The offense will need to keep up with the Nittany Lions attack in order to pull it off, but McNamara’s experience plays to their favor in this one.

For the Nittany Lions, their identity lies on the offensive line where they have very strong protection to help give time in the passing game and open up lanes on the ground. Penn State enters this one undefeated as well, following their victory over Illinois. QB Drew Allar is still inexperienced, but if he can keep rolling against this Hawkeyes stout defense, then Penn State should be able to win this one.

Writer’s Pick: Iowa +4.5

The Hawkeyes are a competitive team, and they often will keep games close. Penn State looks good to start the season, but Iowa should be able to limit the Nittany Lions enough to keep this game close, and cover the spread, take them and the points in this one.

>> Place your wagers at BetOnline

Ole Miss Rebels at Alabama Crimson Tide (Sept. 23rd)

Spread: Alabama -6.5

Analysis: Ole Miss made splashes this offseason with the addition of QBs Spencer Sanders and Walker Howard through the transfer portal. However, incumbent starter Jaxson Dart held onto the job and has looked strong to start the season. Ole Miss is led by RB Quinshon Judkins on offense, and they’ll need them to shine in this one to pull off the victory over the Crimson Tide.

Alabama has had their own much followed QB controversy, but Jalen Milroe has seemed to solidify his position as starter. The Crimson Tide once was a powerhouse across college football, but to this point in the season, they haven’t come across as dominant as they used to be. That doesn’t mean they aren’t plenty capable of handling business in these big time contests, so can the Crimson Tide continue to have their established success against Ole Miss?

Writer’s Pick: Alabama -6.5

Lane Kiffin is 0-3 against Nick Saban during his time at Alabama despite having a few close calls. The Rebels have continued to take some steps in the right direction over the years, but ultimately it’s not a great idea to bet against Saban until further notice. Roll with the Tide and the points here.

>> Start betting on college football week 4 at BUSR

Florida State Seminoles at Clemson Tigers (Sept. 23rd)

Spread: Florida State -2.5

Analysis: Florida State is one of the hottest teams in the country after a big time season opening victory against LSU and continued success in their next two match ups against Southern Miss and Boston College.

The Seminoles have a high-powered offensive attack behind QB Jordan Travis, but the defense is also extremely strong, highlighted by star DE Jared Verse. The Seminoles now come into what could be their tallest task all season, but the season opening victory could play to their favor in this one.

For the Clemson Tigers, they were hit with a big season-opening loss against Duke, but have gotten back on track to win their past two games Charleston Southern and Florida Atlantic. Now though, they go against a scary Florida State squad.

The big player of focus in this one will be CB Nate Wiggins as he will have to handle one of WR Keon Coleman or Johnny Wilson each play, and that will be no easy task. The Tigers have one of the strongest defenses in the country, this one is sure to be a grudge match.

Writer’s Pick: Florida State -2.5

This is no doubt going to be the game with the biggest national spotlight, and there’s a good reason for it. Both teams will compete in this game with a lot at stake fand a ton of history surrounding both programs.

Based off what we’ve seen from these two programs, Florida State seems to offer the more dominant offensive attack, while Clemson’s may continue to struggle here in a big time matchup. If that continues, the Seminoles should be able to score their second big-time victory of the season.

>> Start betting on college football at SportsBetting.ag

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Arkansas Razorbacks at LSU Tigers (Sept. 23rd)

Spread: LSU -4.5

Analysis: Arkansas has one of the most dominant backfield tandems with QB KJ Jefferson and RB Raheim Sanders offering size to scare opponents at the SEC level, and it worked to their favor starting the season 3-0. The offense will be facing their biggest challenge here against LSU, but the Razorbacks offensive line should help set them up for an opportunity to produce in this one and potentially pull off the upset.

For LSU, the expectations were sky-high to start the year, but they fell flat on their face in the season opener against Florida State. They’ve gotten back on track with victories over Grambling State and Mississippi State, but now against Arkansas they’ll have to show much more defensive discipline or they’ll drop their second game of the season.

LSU has looked to have taken a step forward, and they had a similar path last season, so can they repeat that same success?

Writer’s Pick: LSU -4.5

With the ground attack that Arkansas brings to the table, this game is going to be tough. However, LSU has the front seven capable to limit the Arkansas ground attack, and the Razorbacks don’t have the passing game to completely open things up. LSU hasn’t started as strong as expected, but they should show some good signs of life in this as they start to get back on track.

>> Get the latest odds for college football week 4 at BetAnySports

North Carolina Tar Heels at Pittsburgh Panthers (Sept. 23rd)

Spread: North Carolina -6.5

Analysis: QB Drake Maye has been phenomenal up to this point in the season, and the Tar Heels will continue to live and die by his play. With WR Nate McCollum back to help add to the passing attack, the Tar Heels are one of the strongest teams in the ACC and have even looked to be well-balanced through the rest of their roster. This game against the Panthers will be a great in-conference test.

For the Pittsburgh Panthers, they’ve shown some nice promise up to this point in the season and enter this one unbeaten. The Panthers defense is one of the strongest units in the country, and they’ll match up well against this high-powered Tar Heels attack. Stopping them is near impossible, but if they can slow them down, then they could escape with a big time victory.

Writer’s Pick: Pittsburgh +6.5

The Tar Heels likely get away from this one victorious, but Pat Narduzzi is a coach who constantly fields a competitive team. Expect the Panthers to bring some pressure onto Drake Maye and slow down the North Carolina offensive attack. That should do enough for them to cover this spread.

>> Find the latest odds for college football at EveryGame

Memphis Tigers at Missouri Tigers (Sept. 23rd)

Spread: Missouri -6.5

Analysis: The Memphis Tigers have started the season hot with a dynamic ground attack duo between RBs Blake Watson and Sutton Smith. The Tigers have used their offensive ability to clear out the way to a 3-0 season but now hit the road to face off with an impressive SEC Missouri program. The Tigers will need to continue to produce on the ground in order to pull this one out, but with what they’ve shown so far, they’re certainly capable.

For Missouri, they also come into this game with an impressive start after notching a nice upset over Kansas State last weekend. While Memphis may not have the same national attention, this will still be a tough outing for them. The Tigers offense is centered around RB Cody Shrader and WR Luther Burden III, of the Tigers can get them the football in space, then they should be able to handle business in this one.

Writer’s Pick: Missouri -6.5

Missouri will have to slow down the Memphis rushing attack, but they have an impressive defensive unit that gives them the advantage in this one. On the offensive side of things is what should open this one up; if the Tigers can produce through the air, then they should be able to run away with this one and cover the spread on top of it.

>> Place your bets on college football at BetUS

UCLA Bruins at Utah Utes (Sept. 23rd)

Spread: Utah -4.5

Analysis: While a lot of attention will be paid to Oregon-Colorado for Pac 12 games this week, this UCLA-Utah game will also be worth paying attention to. For UCLA, the big story of their season is Freshman QB Dante Moore, who has shown strong signs as the season has kicked off. Now as they enter PAC 12 play, they get the reigning conference champions. This is a tall task for the Bruins, but Head Coach Chip Kelly is plenty capable of handling the pressure.

For the Utes, they’ve notched two Power 5 victories to kick off the season, and they’re feeling good as a result. QB Cam Rising was held out early in the season to heal up, but now that he’s back, the Utes offense should continue to progress as the season continues. Assuming Utah can continue to succeed as they have on the defensive side of the ball, they should be in a good position to win their conference opener.

Writer’s Pick: Utah -4.5

Utah entered this season a bit underestimated due to the questions surrounding QB Cam Rising, but the team proved plenty capable of handling business while he continues his recovery. Now that he’s back and near 100%, the Utes should be able to keep rolling, and that includes covering here against the Bruins.

>> Start betting on college football week 4 at Lucky99

Texas Longhorns at Baylor Bears (Sept. 23rd)

Spread: Texas -7

Analysis: The expectations surrounding the Longhorns are sky high for them to win the Big 12, and they’ll enter conference play going on the road here to face off with the Baylor Bears. The Longhorns identity is their passing attack with star wideouts Xavier Worthy and Adonai Mitchell. The Longhorns have one of the more complete rosters in the country, but last season things went sour after they went on the road in conference play; they need to hold strong in this one.

Speaking of sour, the Bears are off to a rough start to the season, down to 1-2 to start the year and a tough draw to open Big 12 play. Head Coach Dave Aranda is one of the best defensive minds in the country, so bouncing back isn’t off the table. The clock is ticking, though, as a 1-3 start could easily snowball into a bad season.

Writer’s Pick: Texas -7

Baylor looked better last week compared to their 2 week stumble out of the gates, but there are way too many question marks surrounding this squad right now. The Longhorns have the overall roster talent that should keep them clean from this one getting too close, but it won’t be easy in Waco.

>> Find the latest college football odds at XBet

How to Bet on College Football Week 4 – Beginner’s Guide

After breaking down some of Week 4’s biggest games, you’re probably excited to get to betting. However, if you have yet to sign up for an account, then here is a step-by-step guide to get started with one of our most trusted sports betting platforms… Bovada!

Step 1: Register for a Sportsbook Account

Visit Bovada and click the green ‘Join’ button
Fill out all the signup information as needed to register

Step 2: Activate Your Account

Check your email account for the verification link
If you can’t find it, try checking your junk folder
Once you’ve found it, verify your account by clicking the confirmation link

Step 3: Make Your First Deposit

Deposit money into your account using your preferred payment method
Take advantage of the site’s promotional offer

Step 4: Place Your Bets Online

Go to the Sportsbook
Start placing your bets

Best College Football Betting Strategies for Week 4 of the 2023 – 2024 Season

The lines are ready, the games have been reviewed, and you now have your account set up. However, you need to go in with a gameplan. While you can do as you please with your betting, the best chance to succeed at the books is by going in with a strong strategy.

Here are some tips and methods to help give yourself a leg up on the sportsbooks this week.

Emphasis On The Trenches

There are a lot of aspects to consider in every match up, but one of the most important places for teams to win games is on the line of scrimmage. It may be hard to track blocking play and defensive line work without stats but look for seniority and other observations from reporters and other sources to get your information to evaluate which team is better suited to control the game on the inside. It goes a long way on the scoreboard without much attention.

Create An Account With Multiple Sports Books

There are plenty of sportsbooks out there, so looking to find the best odds on each bet you make is smart. By setting up accounts with numerous books, you can cross-reference odds to find the best returns. On top of that, you’ll generally get a signup offer that increases the amount of college football betting funds you’ll have in your account. It’s a no-loss situation!

Take Advantage of Promotional Offers

Sportsbooks love to offer bonuses and boosts on odds in order to ensure they keep their bettors coming back.

You don’t have to take advantage of each promotion, but it’s worth checking them out when you can in order to potentially find some bets that you like. Each week of the football season, there are generally some great offers to increase your winnings should your bet succeed.

Keep these tips in mind for the college football championship, too!

Best Sites to Bet On The 2023-2024 College Football Season

Bovada: Bovada gets lines out quickly every week of the season, perfect for you to make your betting choices early for Week 4 of the college football season. Sign up today, and you could be eligible for a 50% deposit match up to $250 using fiat currency or a 75% match up to $750 with Bitcoin using code BTCSWB750. A 5x rollover applies to both bonuses.

MyBookie: MyBookie is great for finding a large selection of various bets, making finding ones easier for you as a bettor. New users who sign up will be eligible for a 50% deposit match of up to $1,000 with a $50 minimum deposit.

BetOnline: BetOline has great odds on each college football matchup as well as an easy site to navigate, making betting stress-free. Open an account with them today, and you could be eligible for a 50% deposit match up to $1,000, although you’ll have to make a $55 deposit and meet a 10x rollover.

BUSR: BUSR is known for constantly running promotions daily on its site, and that is especially true during the course of the football season. If you decide to register for an account now, you’ll receive a $1,500 welcome bonus.

Sportsbetting.ag: Sportsbetting.ag is constantly on the ball when it comes to live betting, which is perfect to track over the packed college football schedule. New users are eligible for a 50% welcome bonus up to $1,000 using code SB1000, although a $55 minimum deposit and 10x rollover apply.

Guide to Betting on College Football Week 4: FAQs

When Does Week 4 The College Football Season Begin?

Week 4 of the college football season begins Thursday, September 21st, when Coastal Carolina hosts Georgia State in what should be an exciting Sun Belt match up.

Both teams are led by star quarterbacks Grayson McCall and Darren Grainger, so expect this to be a high-scoring affair.

How Long Does A College Football Season Generally Last?

The college football season generally lasts over 15 weeks, but most teams only play games in a 13-week span.

“Week 0” and Week 14 don’t have a lot of games. Most teams will play 12 games for their regular season schedule, with an off week somewhere over the course of the year. However, most teams will play their 12 games sometime over that 13-week span.

Is Betting On College Football Safe?

Betting on College Football is safe as long as you’re using trusted resources to place your bet.

Rolling with one of our recommended sportsbooks is a great way to ensure you can bet safely with security. It is also important that you bet safely and responsibly.

When Is The Deadline To Bet On Week 4 College Football Games?

The deadline to bet on college football for Week 4 is technically at the scheduled kick-off time for each contest.

However, there are live betting options offers with numerous sportsbooks that allow you to place bets during the course of the game. Be aware, though, that the lines and odds could change any second based on in-game events that may take odds out of your favor as a bettor.

Who Is On Upset Alert For Week 4 of College Football?

Outside of the games covered above, there are a few other ranked teams who have some interesting draws for Week 4 of the college football season.

TCU gets a tough draw in SMU, where the Horned Frogs Head Coach Sonny Dykes will face his former team. Oregon State against Washington State should also be an exciting game with some high-powered offensive potential.

Finally, UCF vs. Kansas State should be an excellent battle between two very strong teams. Overall, Week 4 is filled with exciting match ups and should be a great slate of football.

Take a look at our predictions for the previous weeks:

Ready to Bet on Week 4 of the College Football Season?

The college football season continues to move forward, and Week 4 will play a large part in putting together the season’s puzzle. With games that promise to capture plenty of attention across the country and now some betting analysis and research on each game of interest, you’re ready to head to the books and place your bets!

For where you should go to place your bets, we recommend any of the books listed above in the article, especially Bovada! Regardless of where you spend your money this season though, be sure to do so safely and responsibly.

>> Find the latest College Football Week 4 odds at Bovada <<

DISCLAIMER: 21+ only. The information on this site is for entertainment purposes only. Online gambling comes with many risks. Players are advised to gamble responsibly and only use funds they can afford to lose. Remember, gambling is only intended for entertainment purposes and is not a solution to any financial difficulties.

Gambling laws and policies vary from one region to another. Some sites mentioned in this review may not be accessible in your area. Always do your due diligence and check your local gambling policies. It is always better to be safe than sorry.

If you suspect you’re becoming addicted to gambling, seek help immediately by contacting the National Gambling Helpline at 1-800-522-4700.

The following resources may be helpful as well:

College Football Week 4 Point Spreads Overview: Expert Analysis, Predictions, and Latest Odds

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